Rakesh S. Shivatare
JJT University India
Title: Inventing formula for drug development and analytical techniques is the key for pharmaceutical industries
Biography
Biography: Rakesh S. Shivatare
Abstract
The pharmaceutical industry is essentially defined by innovation. Research on the forefront of science, the creation of new knowledge bases, the invention of new medicines, and the improvement of existing drugs constitute the fuel that propels the firms in this industry.
Formulation can be categorized according to the route of administration. Pharmaceutical development information provides the scientific rationale for formulation development and justification for a suitable dosage form. Excipients are the major fraction of the solid dosage forms which serve as diluents to allow the formulation of appropriately sized tablets and coatings to protect the tablet from undesirable organoleptic qualities of the drug substance. Solid state reactions in the dosage form can occur when the drug substance is reactive and may be accelerated by physical and chemical interaction with excipients.
In the field of pharmaceutical research, the analytical investigation of bulk drug materials, intermediates, drug products, drug formulations, impurities and degradation products, and biological samples containing the drugs and their metabolites is very important. From the commencement of official pharmaceutical analysis, analytical assay methods were included in the compendial monographs with the aim to characterize the quality of bulk drug materials by setting limits of their active ingredient content. In recent years, the assay methods in the monographs include titrimetry, spectrometry, chromatography, and capillary electrophoresis; also the electro analytical methods can be seen in the literature.