Gokalp Iscan
Anadolu University, Turkey
Title: Antimicrobial and antioxidant activities of secondary metabolites of endophytic fungi isolated from origanum onites
Biography
Biography: Gokalp Iscan
Abstract
Entophytic fungi live as a symbiotic organisms in higher plants tissues and may improve the host resistance to biotic and abiotic stresses. Endophytes have a very rich biodiversity and they can synthesize so many bioactive secondary metabolites. These natural compounds are challenging potential resources for the pharmaceutical industry. In the present study three endophytic fungi were isolated and subcultured from the leaves of Origanum onites (oregano) and identified by molecular methods. The fungi (Alternaria brassicicola, A. alternata and A. tenuissima) were cultured in liquid media for 14 days and extracted. Crude extracts were analysed with Liquid chromatography/mass spectrometry (LC/MS) system. Furthermore, extracts were evaluated for their antimicrobial and antioxidant effects. Alternaria brassicicola and A. alternata extracts showed significant growth inhibition against selected pathogenes between the concentration range of 7 to 125 µg/mL.