Theme: Modern Innovations in Drug Designing & Broaden the possibilities in Drug Chemistry

Pharm Chem 2019

Pharm Chem 2019

On behalf of ME Conferences, it gives us great pleasure to invite you all to participate in the "21st World Conference On Pharmaceutical Chemistry and Drug Design" which is going to be held during December 09-10, 2019 at Dubai, UAE working under the theme "Modern Innovations in Drug Designing & Broaden the possibilities in Drug Chemistry”. This unique world conference will provide an opportunity to reach the largest assemblage of participants from the Pharmaceutical community to gather and share their insights and convey recent developments in this field. It is a true forum where ideas and discussion is driven by the participants and interaction with peers and others leads to fruitful outcomes.

Why to attend?

Be a part of this exciting event where innovations, advanced practices and researches on various divisions of Pharmaceutical and Drug developments, Novel trends and advanced strategies in Pharma technology, Drug delivery techniques, Recent advancements in Pharma Medicinal Chemistry, Medication of certain diseases and multidisciplinary interventions to promote health and wellness across various populations will be shared and discussed by experts in the field of Medicinal and Pharmaceutical Chemistry. The Scientific program includes Keynote & Plenary talks, Video Presentations, Poster Presentations and E-Posters. Furthermore, Oral communications of doctoral junior scientists will be considered. It is the goal of the organizers to make this meeting an event of scientific excellence, attractive to both industrial and academic scientists in Pharmaceutical chemistry and drug design. 

 Target audience:

  • Nobel laureates
  • Pharmaceutical Researchers
  • Pharmaceutical Industry Professionals (CEOs, MDs, Directors)
  • Academicians (Professors, Deans, Directors)
  • Pharmaceutical Associations and Societies
  • Young Researchers and Students
  • Post- Doctoral
  • Graduates and Post Graduates in Pharmaceutics
  • PhD in Pharmaceutical Sciences
  • Software development companies
  • Government healthcare departments, HTA’s and drug regulators
  • Genomics and personalized medicine experts.

Track 1: Drug Designing

Drug layout is a resourceful procedure of medication observed by means of biological target. It is also recognized as rational drug graph or rational design. The drug is most many times a natural small molecule that prompts or inhibits the function of a biomolecule such as a protein, which in flip outcomes in a therapeutic advantage to the patient. In the most fundamental sense drug graph relies on the knowledge of the three-dimensional structure of bimolecular targets. The drug is an natural molecule, when it is predicament to target  it can either inhibit or set off the feature of a biomolecule which consequences in therapeutic benefit. Drug sketch is an ingenious process of medicinal drug determined by means of organic target. It is also recognised as rational drug design or rational design. The drug is most usually an organic small molecule that activates or inhibits the feature of a biomolecule such as a protein,which in flip effects in a therapeutic gain to the patient. In the most basic sense, drug format depends on the understanding of the three-dimensional structure of bimolecular targets. The drug is a natural molecule, when it is predicament to target it can either inhibit or activate the function of a biomolecule which consequences in therapeutic advantage Pharmaceutical Chemistry Meetings.

Track 2: Pharmaceutical Organic Chemistry

Pharmaceutical organic chemistry is a sub discipline including the logical investigation of the structure, properties, and responses of natural mixes and natural materials, i.e., matter in its different structures that contain carbon molecules. It incorporates numerous physical and substance strategy to decide the compound and materials. Investigation of particles incorporates both physical properties and synthetic properties and utilizations comparative strategies, in order to assess substance reactivity. The assortment of mixes examined in natural science incorporate hydrocarbons, just as organizations dependent on carbon. Moreover, natural science includes further organometallics the lanthanides; however particularly change metals (zinc, copper, nickel, cobalt, titanium and chromium).

The time period drug aims frequently used in medicinal research to describe the native protein in the physique whose undertaking is modified via a drug resulting in a wonderful effect, which may additionally be a perfect therapeutic impact or an undesirable aspect effect. In this context, the organic target is frequently used to as an organic target. The most frequent drug objectives are G-protein couple receptor, enzymes, ligand gated channels, voltage gated channels, ion channels, nuclear.

Track 4: Pharmaceutical Drug Discovery and Nanotechnology

Nanotechnology has now acquainted with create prescription. Nanotechnology contains the utilization of materials with fundamental length scales in the nanometres estimation which exhibit altogether changed properties related to micron organized materials. Such materials can incorporate particles, strands, grain sizes, and so forth. This session featured the movements nanotechnology is making in prescription in such fields as sickness aversion, analysis, and treatment including (however not restricted to) tranquilize revelation, tissue designing, inserts, sensors, disease treatment, a yet not constrained to medicate conveyance, tissue building, transplants, sensors, malignant growth treatment, and poisonous.

Track 5:  Pharmacovigilance

It is that branch of pharmacology that focuses on analysis, detection and prevention of adverse effects caused by pharmaceutics. Adverse drug reactions (ADRs) are a principal motive of patient related mortality.Reporting of ADRs is considered to be an important step in maintaining and achieving a safe drug therapy use. Nowadays, It hugely emphasizes on challenges like Mass treatment regimens, Un-labelled and Off-labelled indications, Nutritional aspects, new drugs, Adherence, Co-morbidities and Drug resistances. Medication errors such as misuse, overdose, abuse of a drug and drug exposure are some of the reasons responsible for ADRs. The main objective is to generate independent, evidence-based recommendations on the safety of medicines and to monitor benefit-risk profile of different pharmaceutics.

Track 6: Enzyme Reaction

Enzyme reaction is the extend in the quantity of a chemical response by using protein. The protein catalyst (enzyme) may be phase of a multi-subunit compound, and or can also rapidly or permanently partner with a Cofactor (example, xylose). Catalysis of enzyme reactions due to the very low response charges of the uncatalyzed reactions at room temperature and pressure. A major driver of protein development is the optimization of such catalytic things to do by way of protein dynamics. The mechanism of enzyme catalysis is analogous in principle to different types of chemical catalysis. By furnished that an alternative response routes the enzyme reduces the strength required to reach the perfect strength transformation country of the reaction. The reduction of activation electricity will increase the volume of reactant molecules that reap an adequate stage of energy, such that they reach the activation energy and structure the product.

Track 7: Materialistic Chemistry & Synthetic Chemistry

The character of particles and the progressions that happen at research of such components on the atomic dimension and non-naturalchemistry of nanomaterials. On the other hand, change of peptide materials by Thiol-X science also includes the procedures of those substances which are endued with inherent voids, perfect materials, and genuine materials. Natural science isn't simply included with the disclosure of organic wonders to Materialistic Chemistry is a control of outskirts in inorganic engineered science that looks to uncover use the investigations of medication structure and medication revelation.

Track 8: Cancer Research in Medicinal Chemistry

The expression "malignancy" alludes to a gathering of maladies that incorporate sporadic cell development with the inert spread to different pieces of the body. As every malignant growth comprises of a different cell types very viable at creating showdown to both medication and radiation treatment, it is an especially troublesome sickness to treat. The test for the field of therapeutic science is to configuration drugs prepared to do specifically focusing on malignant growth cells while dodging multidrug opposition pathways. Utilizing late perceptions into the one of kind qualities of malignant growth cells, Medicinal Chemistry is seeking after enemy of tumor specialists of high explicitness to help configuration fittingly focused on, specific chemotherapeutics. Current projects include a different exhibit of against malignant growth targets, for example, lipid and protein kinases, microtubules, topoisomerases, and hypoxia inducible elements.

Track 9: Computer Aided Drug Design

Computer aided drug design and Advanced Instrumentation is that the most fundamental purpose is to predict whether or not a given bioactive molecule can bind to a target or not. Study in drug graph or biomarkers in drug layout measures the conformation of the little molecule and to model conformational modifications within the biological target which will manifest as soon as the little molecule binds thereto. Recent advances in CADD with the utilization of excessive performance computing science and Insilco molecular graph pc code and tools offer would possibly optimize the parameters for the molecular mechanics calculations and moreover grant an estimation of the electronic properties (electrostatic potential, polarizability) of the drug molecule that may also impact binding affinity within the use of ultrasound in medicinal chemistry. High-resolution 1H-NMR chemical analysis and X-Ray absorption chemical analysis method might also moreover be accustomed offer semi-quantitative prediction of the required affinity.

Track 10: Pharma Medicinal Chemistry

The margins between present developments in medicinal chemistry and investigative medicinal chemistry between inanimate and dwelling depend may additionally be a principal feature of the convergence between engineering and biotechnology. The most intention of current advances in medicinal chemistry is to emphasize that even though growing life may be a persistent task which measures subtle method within the underlying hypothetical assumptions. This contrast is supposed to make contributions to an extended understanding of the cultural issues at stake inside the convergence between nano and biotechnologies. It suggests that the limit between life and in animate matter remains a stock in which the advancement in Pharmacogenomics and Pharmacoproteomic two two lookup on tablets will tends to new discoveries.

Track 11: Chemoinformatic Drug Discovery

Chemoinformatics plays a vital link between made-up design and in drug design through mining of information from the data and translate into knowledge. Derivation of information and knowledge is only one aspect of chemoinformatic. The use of consequent knowledge in a design and selection support role is an important part of the drug design cycle. The main processes within drug discovery are lead documentation, where a lead is something that has activity in the low micro molar range, and lead optimization, which is the process of transforming a lead into a drug candidate. Chemo informatics methods can be used proactively to designing and filter the most appropriate compounds to work within the real world.

Track 12: Clinical Trials and Regulatory Affairs in Pharmacy

Clinical trials are tests achieved in clinical research. Such remaining biomedical or interactive research on human individuals are designed to reply questions about biomedical or behavioural interferences, with new redress (such as novel vaccines, drugs, dietary choices, dietary supplements, and scientific devices) and recognised interventions that certification similarly learn about and comparison. Clinical trials generate information on security and efficacy. Regulatory affairs are definitely a new career which established from the wish of governments to tightly closed public health by way of monitoring the protection and price of products in areas collectively with pharmaceutical, pesticides, medical devices, agrochemicals, cosmetics and different related medicines.

Track 13: Novel Drug Target Approaches

Categorizing drug targets performs essential roles in designing new pills and opposing diseases. Unfortunately, our modern understanding about drug pursuits is far from complete. Screening drug ambitions in the lab is an expensive and time-consuming procedure. In the past decade, the accumulation of a number types of study of science associated data makes it feasible to boost computational methods to predict drug targets. Non-communicable ailments such as cancer, atherosclerosis and diabetes are responsible for most vital social and health disease as thousands and thousands of people are loss of life each and every year. Out of which, atherosclerosis is the leading motive of deaths globally. The lipid irregularity is one of the most essential adjustable danger factors for atherosclerosis. Both genetic and conservation aspects are related with the improvement of atherosclerotic signs.

Track 14: Novel Drug Delivery System in Pharmaceutics

The system via which a drug is dispensed can have an essential effect on its efficiancy. Some pills have an finest awareness range inside which  is derived, and concentrations above or under this vary can be noxious or produce no therapeutic advantage at all. On the different hand, the very slow improvement in the efficacy of the treatment of extreme diseases, has optionally available a developing need for a multidisciplinary approach to the shipping of therapeutics to objectives in tissues. These nanoparticles would be loaded with capsules and plagued to precise components of the body the place there is definitely diseased tissue, thereby fending off interplay with wholesome tissue. The goal of a focused drug shipping gadget is to extend, localize, goal and have vulnerable drug interplay with the diseased muscle.

TRACK 15: Proteomics & Bioinformatics Drug Discovery

Proteomics, the large-scale analysis of proteins, contributes expressively to our understanding of gene function in the post-genomic era. Proteomics can be divided into three main areas: (1) protein micro-characterization for large-scale certification of proteins and their post-translational changes; (2) differential display' proteomics for comparison of protein levels with potential application in a extensive range of diseases; and (3) studies of protein–protein interactions using methods such as mass spectrometry or the yeast two-hybrid system. Proteomics technologies are under nonstop progresses and new skills are introduced. Nowadays high quantity acquisition of proteome data is possible.

Track 16: Pharmacy Marketing

The Present Marketing practice in the Pharmaceutical sector, examining both customer and doctor slanted towards promotion. The present examples of marketing practices and their impact on consumer and doctor behavior. It identifies negative impact of these practices which include misleading advertising, disease shove and escalating costs. It goes on to maintain the need for an independently monitored code of practice for marketers in the pharmaceutical sector and a great degree of consumer education for both end users and those Prescribing drugs.

Scope and Importance:

The pharmaceutical business speaks to a standout among the most dynamic and requesting ventures on the planet. As human services keep on developing and record for a noteworthy bit of the economy in the United States and all through the world, the significance of the pharmaceutical and social insurance industry increments. The Pharma Industry are in charge of advancement, generation and advertising of drugs. Throughout the years drug store has developed as pharmaceuticals sciences through innovative work forms. It is identified with item and in addition to administrations. The different medications found and created are its items and the human services it gives goes under the class of administrations.
 
Why in Dubai?

Dubai is the most crowded city in the United Arab Emirates (UAE). It is located on the southeast shore of the Persian Gulf and is one of the seven emirates that make up the nation. The city of Dubai is located on the emirate's northern seashore and heads up the Dubai-Sharjah-Ajman metropolitan territory. Dubai is to host World Expo 2020.Dubai has risen as a worldwide city and business center of the Middle East. It is additionally a noteworthy transport center for travelers and payload. The most understood colleges in Dubai are American University in Dubai, Halt International Business School, Al Ghurair University, The American College of Dubai, University of Wollongong in Dubai, British University in Dubai offering courses in Business Administration, Engineering, Architecture and Interior Design. American University in Dubai is one of the six UAE colleges highlighted in QS World University Rankings 2014/2015. In 2013 Synergy University Dubai Campus opened its grounds in Jumeirah Lakes Towers being a first University in Dubai to situated outside of Educational Zones.

Pharmaceutical Excipients:

The global pharmaceutical excipients market is projected to reach USD 517 billion in 2022 at a CAGR of 11.9% from the fore cast period of 2018 to 2022.The rising demand for new drug delivery system, is greater of functional benefits of excipients, growing pharmaceutical Industry, and patient expires of several drugs are positively impacting the overall growth in market.

Pharma Market in Dubai:

The most advanced markets in the Middle East, is the UAE Pharma market, associated with a sturdy expenditure of perfect per-capita medicinal drug and fundamentals of healthcare in the Middle East. The Dubai Health Authority has been working on developing the scientific tourism sector. The intention is to probably attract 1.3 million medical travellers yearly through 2021. The income generated via clinical tourism is predicted to develop via 13% yearly constantly over the subsequent five years. As per studies it has been published that Dubai has skilled a sturdy development in pharmaceutical trading. Imports of pharmaceutical merchandise have risen from Dhs100m to Dhs400m in 2003, whilst in 2010 exports too accelerated from Dhs800m to Dhs3bn. Thereby finalizing the status; Industry specialists say that there is viable for exponential increase in the pharmaceutical products sector.

Generic drug analysis

The United States and Europe has most of the main pharmaceutical companies. Largest share of pharmaceutical income is made by using branded and patented medicines. In 2016 an anti-inflammatory drug generated over 16 billion U.S. bucks of income globally. Oncologics proceed to be one of the three leading therapeutic instructions based totally on revenue. Cancer tablets made almost seventy nine billion U.S. greenbacks of revenue global in 2015. Other most important therapy training were ache drugs, anti-hypertensive and anti-diabetics.

Radiopharma Market analysis

The world market Radiopharmaceuticals have been valued at nearly $5.1 billion and $5.7 billion in 2014 and 2015, respectively. This market is expected to amplify from nearly $6.5 billion in 2016 to $11.6 billion in 2021 at a compound annual growth charge (CAGR) of 12.4% for 2016-2021.

Related Societies:

EUROPE:

USA:

New York Health Products Council; Pharmaceutical Research and Manufacturers of America ;American Association of Colleges of Pharmacy; American Society of Consultant Pharmacists ; American Society of Health-System Pharmacists;  International Pharmaceutical Federation; Drug Information Association.

MIDDLE EAST:

Scientific Centre of Drug and Medical Technology Expertise;Egyptian Drug Authority Georgia Drugs ;Pharmacy and Drug Control

ASIA:
 

List of Pharmaceutical Companies in Dubai:

  • Pharma Service Company
  • Globalpharma - A Sanofi Company
  • Pfizer
  • Pharma trade L.L.C.
  • Clinart International
  •  Aster (Aster One) Pharmacy
  • IDS - Al I tithed Drug Store
  • Genpharm
  • Ranbaxy Laboratories Limited
  • BioPharma
  • GlaxoSmithKlin

 

Conference Highlights

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Conference Date December 09-10, 2019
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